Recombinant Human glycolipid transfer protein domain containing 1, His-tagged

• Cat.No.: GLTPD1-607H
• Product Overview: GLTPD1, 1-214aa, Human, His tag, E.coli

Specification

• Description: GLTPD1 mediates the intracellular transfer of ceramide-1-phosphate between organelle membranes and the cell membrane. This protein is required for normal structure of the Golgi stacks. GLTPD1 can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0). It plays a role in the regulation of the cellular levels of ceramide-1-phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity and the release of arachidonic acid. Recombinant human GLTPD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In Phosphate buffered saline (pH7.4) containing 50% glycerol, 1mM DTT
• Molecular Mass: 26.8 kDa (237aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDDSETG FNLKVVLVSF KQCLDEKEEV LLDPYIASWK GLVRFLNSLG TIFSFISKDV VSKLRIMERL RGGPQSEHYR SLQAMVAHEL SNRLVDLERR SHHPESGCRT VLRLHRALHW LQLFLEGLRT SPEDARTSAL CADSYNASLA AYHPWVVRRA VTVAFCTLPT REVFLEAMNV GPPEQAVQML GEALPFIQRV YNVSQKLYAE HSLLDLP
• Purity: >90 % by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: GLTPD1?glycolipid transfer protein domain containing 1 [?Homo sapiens(human) ]
• Official Symbol: GLTPD1
• Synonyms: GLTPD1; CPTP; glycolipid transfer protein domain containing 1; ceramide-1-phosphate transfer protein; GLTP domain-containing protein 1; glycolipid transfer protein domain-containing protein 1
• Gene ID: 80772
• mRNA Refseq: NM_001029885
• Protein Refseq: NP_001025056
• MIM: 615467
• UniProt ID: Q5TA50
• Chromosome Location: 1p36.33
• Function: ceramide 1-phosphate binding; ceramide 1-phosphate transporter activity; glycolipid binding