"GTF2H5" Related Products

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Recombinant Human general transcription factor IIH, polypeptide 5, His-tagged

Cat.No.: GTF2H5-659H
Product Overview: GTF2H5, 1-71aa Human, His tag, E.coli
Description: GTF2H5 is a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. Recombinant human GTF2H5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid, In Phosphate buffered saline (pH7.4) containing 10% glycerol
Molecular Mass: 10.4 kDa (94aa) confirmed by MALDI-TOF
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMVNVLKG VLIECDPAMK QFLLYLDESN ALGKKFIIQD IDDTHVFVIA ELVNVLQERV GELMDQNAFS LTQK
Purity: >95 % by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 1.0 mg/ml (determined by Bradford assay)
Gene Name: GTF2H5 general transcription factor IIH, polypeptide 5 [ Homo sapiens (human) ]
Official Symbol: GTF2H5
Synonyms: GTF2H5; TTD; TFB5; TTDA; TFIIH; TTD-A; TGF2H5; C6orf175; bA120J8.2; general transcription factor IIH, polypeptide 5; general transcription factor IIH subunit 5; TFB5 ortholog; TFIIH basal transcription factor complex TTDA subunit; TFIIH basal transcription factor complex TTD-A subunit
Gene ID: 404672
mRNA Refseq: NM_207118
Protein Refseq: NP_997001
MIM: 608780
UniProt ID: Q6ZYL4
Chromosome Location: 6q25.3
Pathway: Basal transcription factors; Holo-TFIIH complex; Nucleotide excision repair

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