Recombinant Human ATOX1 Protein, with Cu (I)
Cat.No. : | ATOX1-225H |
Product Overview : | Recombinant full length Human Cu (I)-ATOX1 (aa 1-68) was expressed in E. coli. Binding of Cu (I) to the protein was confirmed by ICP. |
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Description : | This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. |
Source : | E. coli |
Species : | Human |
Form : | In 20 mM Phosphate buffer pH 7.0. |
Molecular Mass : | 7.4 kDa |
Protein length : | aa 1-68 |
AA Sequence : | MPKHEFSVDM TCGGCAEAVS RVLNKLGGVK YDIDLPNKKV CIESEHSMDT LIATLKKTGK TVSYLGLE |
Purity : | >95% by SDS-PAGE. The protein was observed as a single band migrating at a molecular weight < 10 kDa. |
Notes : | To avoid oxidation and leaking of the Cu(I) bound to the protein, keep and use the sample under inert atomosphere. |
Storage : | Store at - 20 centigrade. The protein is stable at 4 centigrade for at least 2 weeks and at 25 centigrade for at least several hours. After initial deforst, aliquot product into individual tubes under inert atomosphere and refreeze at - 20 centigrade. Avoid repeated freeze/defrost cycles. Avoid exposition to air. |
Concentration : | 1 mg/ml |
Gene Name : | ATOX1 ATX1 antioxidant protein 1 homolog (yeast) [ Homo sapiens ] |
Official Symbol : | ATOX1 |
Synonyms : | ATOX1; ATX1 antioxidant protein 1 homolog (yeast); ATX1 (antioxidant protein 1, yeast) homolog 1; copper transport protein ATOX1; HAH1; metal transport protein ATX1; ATX1; MGC138453; MGC138455; |
Gene ID : | 475 |
mRNA Refseq : | NM_004045 |
Protein Refseq : | NP_004036 |
MIM : | 602270 |
UniProt ID : | O00244 |
Chromosome Location : | 5q32 |
Pathway : | Mineral absorption, organism-specific biosystem; Mineral absorption, conserved biosystem; |
Function : | copper chaperone activity; copper ion binding; copper-dependent protein binding; metal ion binding; metallochaperone activity; |
Products Types
◆ Recombinant Protein | ||
ATOX1-506R | Recombinant Rat ATOX1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATOX1-840M | Recombinant Mouse ATOX1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATOX1-2100M | Recombinant Mouse ATOX1 Protein | +Inquiry |
ATOX1-958H | Recombinant Human ATOX1 protein, GST-tagged | +Inquiry |
ATOX1-850R | Recombinant Rat ATOX1 Protein | +Inquiry |
◆ Lysates | ||
ATOX1-8616HCL | Recombinant Human ATOX1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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