Recombinant Human EDNRB, Fc-tagged

• Cat.No.: EDNRB-272H
• Product Overview: A DNA sequence encoding the human EDNRB (NP_000106.1) (Met1-Lys101) was expressed with the Fc region of mouse IgG1 at the C-terminus.

Specification

• Source: Human Cells
• Species: Human
• Tag: Fc
• Form: Lyophilized from sterile PBS, pH7.4.
• Molecular Mass: The recombinant human EDNRB/mFc comprises 309 amino acids and has a predicted molecular mass of 34.4 kDa. The apparent molecular mass of the protein is approximately 47.5 and 43.7 kDa in SDS-PAGE under reducing conditions.
• Protein length: Met1-Lys101
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >85 % as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70℃
• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: EDNRB endothelin receptor type B [ Homo sapiens ]
• Official Symbol: EDNRB
• Synonyms: EDNRB; endothelin receptor type B; HSCR, HSCR2; endothelin B receptor; ETB; endothelin receptor non-selective type; ET-B; ETBR; ETRB; HSCR; WS4A; ABCDS; ET-BR; HSCR2
• Gene ID: 1910
• mRNA Refseq: NM_000115
• Protein Refseq: NP_000106
• MIM: 131244
• UniProt ID: P24530
• Chromosome Location: 13q22
• Pathway: Arf6 trafficking events, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Endothelins, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem
• Function: G-protein coupled receptor activity; endothelin receptor activity; endothelin receptor activity; endothelin receptor activity; peptide hormone binding; receptor activity; signal transducer activity