"MUC1" Related Products

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Recombinant Human MUC1, Fc-tagged

Cat.No.: MUC1-342H
Product Overview: A DNA sequence encoding the human MUC1 isoform 2 (NP_001018016.1) extracellular domain (Met1-Gly167) was fused with the Fc region of mouse IgG at the C-terminus.
Source: Human Cells
Species: Human
Tag: Fc
Form: Lyophilized from sterile PBS, pH7.4.
Molecular Mass: The recombinant human MUC1/mFc is a disulfide-linked homodimer. The reduced monomer consists of 369 amino acids after removal the signal peptide and has a predicted molecular mass of 41 kDa. As a result of glycosylation, rhMUC1/mFc monomer migrates as an approximately 50.2 and 34.8 kDa band in SDS-PAGE under reducing conditions.
Protein length: Met1-Gly167
Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
Purity: ( 84.9+9.2) % as determined by SDS-PAGE
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name: MUC1 mucin 1, cell surface associated [ Homo sapiens ]
Official Symbol: MUC1
Synonyms: MUC1; mucin 1, cell surface associated; mucin 1, transmembrane , PUM; mucin-1; CD227; PEM; episialin; DF3 antigen; H23 antigen; krebs von den Lungen-6; mucin 1, transmembrane; tumor-associated mucin; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; EMA; PUM; KL-6; MAM6; PEMT; H23AG; MUC-1; MUC-1/X; MUC1/ZD; MUC-1/SEC;
Gene ID: 4582
mRNA Refseq: NM_001018016
Protein Refseq: NP_001018016
MIM: 158340
UniProt ID: P15941
Chromosome Location: 1q22
Pathway: IL-7 Signaling Pathway, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; O-linked glycosylation of mucins, organism-specific biosystem; Post-translational protein modification, organism-specific biosystem; T Cell Receptor Signaling Pathway, organism-specific biosystem; Termination of O-glycan biosynthesis, organism-specific biosystem;
Function: RNA polymerase II core promoter proximal region sequence-specific DNA binding; p53 binding; protein binding; transcription cofactor activity;

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