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Recombinant Human KLRK1, Fc-tagged

Cat.No.: KLRK1-350H
Product Overview: A DNA sequence encoding the human NKG2D (NP_031386.2) (Phe78-Val216) was expressed with the Fc region of human IgG1 at the N-terminus.
Source: CHO Stable Cells
Species: Human
Tag: Fc
Form: Lyophilized from sterile PBS, pH7.4.
Bio-activity: Immobilized human ULBP1-His at 10 μg/ml (100 μl/well) can bind human S4-Fc3L3-NKG2D, The EC50 of human S4-Fc3L3-NKG2D is 0.39-0.91 μg/ml.
Molecular Mass: The recombinant human NKG2D/Fc comprises 418 amino acids and has a predicted molecular mass of 46.5 kDa. The apparent molecular mass of the protein is approximately 50-64 and 37 kDa in SDS-PAGE under reducing conditions.
Protein length: Phe78-Val216
Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
Purity: (81.4+13.9) % as determined by SDS-PAGE
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name: KLRK1 killer cell lectin-like receptor subfamily K, member 1 [ Homo sapiens ]
Official Symbol: KLRK1
Synonyms: KLRK1; killer cell lectin-like receptor subfamily K, member 1; D12S2489E, DNA segment on chromosome 12 (unique) 2489 expressed sequence; NKG2-D type II integral membrane protein; CD314; KLR; NKG2 D; NKG2D; NK cell receptor D; NKG2-D-activating NK receptor; NKG2-D; D12S2489E; FLJ17759; FLJ75772;
Gene ID: 22914
mRNA Refseq: NM_007360
Protein Refseq: NP_031386
MIM: 611817
UniProt ID: P26718
Chromosome Location: 12p13.2-p12.3
Pathway: Adaptive Immune System, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; Malaria, organism-specific biosystem; Malaria, conserved biosystem; Natural killer cell mediated cytotoxicity, organism-specific biosystem; Natural killer cell mediated cytotoxicity, conserved biosystem;

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