Recombinant Human PCTK2 (CDK17), GST-tagged

• Cat.No.: CDK17-56H
• Product Overview: Recombinant full-length human PCTK2 (CDK17) and Cyclin Y (2-end) were co-expressed by baculovirus in Sf9 insect cells using N-terminal GST tags.

Specification

• Description: PCTK2 (CDK17) or cyclin-dependent kinase 17 belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. PCTK2 has similarity to a rat protein that is thought to play a role in terminally differentiated neurons. The identification of a large family of cdc2-related kinases opens the possibility of combinatorial regulation of the cell cycle together with the emerging large family of cyclins.
• Source: Sf9 insect cells using baculovirus
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: PCTK2 (CDK17) ~ 88 kDa and Cyclin Y ~ 64 kDa
• Applications: Kinase Assay, Western Blot
• Storage: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: CDK17 cyclin-dependent kinase 17 [ Homo sapiens ]
• Official Symbol: CDK17
• Synonyms: CDK17; cyclin-dependent kinase 17; PCTAIRE protein kinase 2 , PCTK2; PCTAIRE2; PCTAIRE-motif protein kinase 2; cell division protein kinase 17; protein kinase cdc2-related PCTAIRE-2; serine/threonine-protein kinase PCTAIRE-2; PCTK2
• Gene ID: 5128
• mRNA Refseq: NM_001170464
• Protein Refseq: NP_001163935
• MIM: 603440
• UniProt ID: Q00537
• Chromosome Location: 12q23.1
• Function: ATP binding; cyclin-dependent protein kinase activity; nucleotide binding; protein kinase activity