Recombinant Human ACAT1, His-tagged ACAT1-3045H

Recombinant Human ACAT1, His-tagged


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Recombinant Human ACAT1, His-tagged

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Cat.No. : ACAT1-3045H
Product Overview : ACAT1
Description : This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. [provided by RefSeq, Feb 2009]
Source : E. Coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl, 10% glycerol, 1mM DTT
Molecular Mass : 43.8kDa (417aa) confirmed by MALDI-TOF
Protein length : 427
Purity : >95% by SDS - PAGE
Applications : SDS-PAGE
Notes : Small volumes of ACAT1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Warning : This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name : ACAT1 acetyl-CoA acetyltransferase 1 [ Homo sapiens ]
Official Symbol : ACAT1
Synonyms : ACAT1; acetyl-CoA acetyltransferase 1; ACAT, acetyl Coenzyme A acetyltransferase 1; acetyl-CoA acetyltransferase, mitochondrial; acetoacetyl Coenzyme A thiolase; THIL; acetoacetyl-CoA thiolase; acetyl-Coenzyme A acetyltransferase 1; mitochondrial acetoacetyl-CoA thiolase; T2; MAT; ACAT;
Gene ID : 38
mRNA Refseq : NM_000019
Protein Refseq : NP_000010
MIM : 607809
UniProt ID : P24752
Chromosome Location : 11q22.3
Pathway : Branched-chain amino acid catabolism, organism-specific biosystem; Butanoate metabolism, organism-specific biosystem; Butanoate metabolism, conserved biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, organism-specific biosystem; C5 isoprenoid bio
Function : acetyl-CoA C-acetyltransferase activity; coenzyme binding; enzyme binding; metal ion binding; protein homodimerization activity; transferase activity, transferring acyl groups other than amino-acyl groups;

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