Recombinant Human SLC33A1, His-tagged

• Cat.No.: SLC33A1-3052H
• Product Overview: Acetyl-coenzyme A transporter 1 (SLC33A1)

Specification

• Description: The protein encoded by this gene is required for the formation of O-acetylated (Ac) gangliosides. The encoded protein is predicted to contain 6 to 10 transmembrane domains, and a leucine zipper motif in transmembrane domain III. Defects in this gene have been reported to cause spastic paraplegia autosomal dominant type 42 (SPG42) in one Chinese family, but not in similar patients of European descent. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
• Source: E. Coli or Yeast
• Species: Human
• Tag: His
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Protein length: 549
• Purity: >90%
• Notes: Small volumes of SLC33A1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 [ Homo sapiens ]
• Official Symbol: SLC33A1
• Synonyms: SLC33A1; solute carrier family 33 (acetyl-CoA transporter), member 1; ACATN, acetyl Coenzyme A transporter , spastic paraplegia 42 (autosomal dominant) , SPG42; acetyl-coenzyme A transporter 1; AT 1; AT1; AT-1; ACATN; SPG42; CCHLND
• Gene ID: 9197
• mRNA Refseq: NM_001190992
• Protein Refseq: NP_001177921
• MIM: 603690
• UniProt ID: O00400
• Chromosome Location: 3q25.31
• Pathway: Glycosphingolipid biosynthesis - ganglio series, organism-specific biosystem; Glycosphingolipid biosynthesis - ganglio series, conserved biosystem; Metabolic pathways, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific bi
• Function: acetyl-CoA transporter activity