Recombinant Human ASMT, His-tagged

• Cat.No.: ASMT-3063H
• Product Overview: Acetylserotonin O-methyltransferase (ASMT)

Specification

• Description: This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene.
• Source: E. Coli or Yeast
• Species: Human
• Tag: His
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Protein length: 373
• Purity: >90%
• Notes: Small volumes of ASMT recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: ASMT acetylserotonin O-methyltransferase [ Homo sapiens ]
• Official Symbol: ASMT
• Synonyms: ASMT; acetylserotonin O-methyltransferase; ASMTY; HIOMT; HIOMTY; hydroxyindole O-methyltransferase; acetylserotonin N-methyltransferase; acetylserotonin methyltransferase (Y chromosome)
• Gene ID: 438
• mRNA Refseq: NM_001171038
• Protein Refseq: NP_001164509
• MIM: 300015
• UniProt ID: P46597
• Chromosome Location: Xp22.3 and Yp11.3
• Pathway: Amine-derived hormones, organism-specific biosystem; Biogenic Amine Synthesis, organism-specific biosystem; Melatonin biosynthesis, tryptophan =>serotonin => melatonin, organism-specific biosystem; Melatonin biosynthesis, tryptophan => serotonin =&
• Function: O-methyltransferase activity; acetylserotonin O-methyltransferase activity; transferase activity