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Recombinant Mouse Alkbh1, His-tagged

Cat.No. : Alkbh1-3273M
Product Overview : Alkylated DNA repair protein alkB homolog 1 (Alkbh1)
  • Specification
  • Gene Information
  • Related Products
Source : E. Coli or Yeast
Species : Mouse
Tag : His
Form : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Protein length : 389
Purity : >90%
Notes : Small volumes of Alkbh1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage : Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Storage Buffer : PBS pH 7.4, 50% glycerol
Warning : This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name : Alkbh1 alkB, alkylation repair homolog 1 (E. coli) [ Mus musculus ]
Official Symbol : Alkbh1
Synonyms : ALKBH1; alkB, alkylation repair homolog 1 (E. coli); alkylated DNA repair protein alkB homolog 1; DNA lyase ABH1; alpha-ketoglutarate-dependent dioxygenase ABH1; Abh; alkB; hABH; Alkbh; 2700073G19Rik;
Gene ID : 211064
mRNA Refseq : NM_001102565
Protein Refseq : NP_001096035
Function : DNA-(apurinic or apyrimidinic site) lyase activity; catalytic activity; chemoattractant activity; ferrous iron binding; lyase activity; metal ion binding; methylcytosine dioxygenase activity; oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (17)

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How does ALKBH1 participate in DNA base repair and oxidative stress? 06/16/2022

ALKBH1 can remove oxidative components and methylation markers from DNA, and is involved in DNA base repair and oxidative stress.

How to evaluate the expression and role of ALKBH1 in liver cancer? 12/23/2021

By studying the expression and function of ALKBH1 in liver cancer tissue, we can understand its role in the treatment of liver cancer.

In which tissues is ALKBH1 expressed? 11/25/2021

ALKBH1 is mainly expressed in liver, spleen, myocardium and other tissues.

What is the role of ALKBH1 in the occurrence and development of gastric cancer? 11/01/2021

ALKBH1 plays a key role in the development and progression of gastric cancer, which may be related to the regulation of DNA repair and apoptosis.

What is the significance of changes in ALKBH1 expression for the prediction of metabolic diseases? 09/08/2021

The study on the expression level of ALKBH1 in metabolic diseases can provide new ideas for the prediction and treatment of metabolic diseases.

How does ALKBH1 affect the immune system and inflammatory response? 04/17/2021

It can influence the function of the immune system and the occurrence of inflammatory responses, regulating cell state by removing oxidative components and methylation markers.

What is the role of ALKBH1 in nervous system and related diseases? 04/14/2021

It has been shown to play an important role in neurological and related disorders, including mild cognitive impairment.

Is ALKBH1 expression regulated by environmental factors and endogenous signals? 03/16/2021

The expression may be regulated by various environmental factors and endogenous signals, including chemical stimulation and oxidative stress.

What is the role of ALKBH1 in DNA damage repair? 02/08/2021

ALKBH1 plays a key role in DNA damage and repair, repairing 1- or 3-methyladenine in DNA.

What is the role of ALKBH1 in cardiovascular disease? 12/01/2020

This protein plays an important role in the occurrence and development of cardiovascular diseases, which may be related to lipid metabolism and pathway regulation.

Which method does ALKBH1 in mammalian stem cell reprogramming? 09/29/2020

ALKBH1 plays an important role in mammalian stem cell reprogramming, promoting stem cell proliferation and differentiation.

Which effect of ALKBH1 mutation on metabolic capacity? 08/22/2020

The mutation may affect metabolic capacity and cause liver disease, diabetes, obesity and other related diseases.

How does ALKBH1 participate in DNA methylation repair? 04/17/2020

It can remove 1- or 3-methyladenine from DNA and is involved in DNA methylation repair and DNA repair processes.

What diseases are ALKBH1 mutations associated with? 03/12/2020

The mutation may be associated with cancer, cardiovascular disease, liver disease, etc.

What is the enzyme activity mechanism of ALKBH1? 01/18/2020

ALKBH1 repairs DNA damage by removing 1- or 3-methyladenine from DNA double-stranded DNA in an oxygen-dependent manner.

How to study the expression and role of ALKBH1 in certain diseases? 06/14/2019

The expression and role of ALKBH1 in certain diseases can be comprehensively evaluated through comparative omics, immunopathology, molecular biology and other research methods, so as to provide references for disease prediction and treatment.

Which cell signal transduction pathways does ALKBH1 participate in? 06/10/2019

ALKBH1 is involved in a variety of cell signaling pathways, including NF-κB.

Customer Reviews (4)

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Reviews
12/17/2020

    Can meet the specific experimental requirements and research purposes when used in experiments.

    05/16/2020

      The products are available in a wide range of specifications for different sizes and experimental designs.

      04/18/2020

        When ALKBH1 was used in the experiment, clear and consistent results could be obtained, which was convenient for data analysis and interpretation.

        12/24/2019

          Long half-life and is able to maintain stability and reliability during the experiment.

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