Recombinant Human SCNN1G, His-tagged

• Cat.No.: SCNN1G-3417H
• Product Overview: Amiloride-sensitive sodium channel subunit gamma (SCNN1G)

Specification

• Description: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome.
• Source: E. Coli or Yeast
• Species: Human
• Tag: His
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Protein length: 649
• Purity: >90%
• Notes: Small volumes of SCNN1G recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: SCNN1G sodium channel, non-voltage-gated 1, gamma subunit [ Homo sapiens ]
• Official Symbol: SCNN1G
• Synonyms: SCNN1G; sodium channel, non-voltage-gated 1, gamma subunit; sodium channel, non voltage gated 1, gamma , sodium channel, nonvoltage gated 1, gamma; amiloride-sensitive sodium channel subunit gamma; ENaCgamma; SCNEG; gamma-ENaC; gamma-NaCH; ENaC gamma subunit; epithelial Na(+) channel subunit gamma; sodium channel, nonvoltage-gated 1, gamma; nonvoltage-gated sodium channel 1 subunit gamma; amiloride-sensitive sodium channel gamma-subunit; amiloride-sensitive epithelial sodium channel gamma subunit; PHA1; BESC3; ENaCg
• Gene ID: 6340
• mRNA Refseq: NM_001039
• Protein Refseq: NP_001030
• MIM: 600761
• UniProt ID: P51170
• Chromosome Location: 16p12
• Pathway: Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Taste transduction, organism-specific biosystem; Taste transduction, conserved biosystem
• Function: WW domain binding; ion channel activity; ligand-gated sodium channel activity; protein binding; sodium channel activity