Native Human ApoA-II

• Cat.No.: ApoA-II-3555H

Specification

• Description: This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.
• Source: Human plasma
• Species: Human
• Form: Supplied as frozen liquid in 10mM NH4HC03 buffer, pH 7.4. Keep antigen concentration >1 mg/ml
• Molecular Mass: 17.4 kDa
• Purity: >95% pure by SDS PAGE
• Notes: Small volumes of ApoA-II native protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Aliquot and store at -70 deg C. Avoid repeated freeze/thaw cycles
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: APOA2 apolipoprotein A-II [ Homo sapiens ]
• Official Symbol: APOA2
• Synonyms: APOA2; apolipoprotein A-II; apolipoprotein A2; apoAII; Apo-AII; ApoA-II
• Gene ID: 336
• mRNA Refseq: NM_001643
• Protein Refseq: NP_001634
• UniProt ID: P02652
• Chromosome Location: 1q21-q23
• Pathway: Chylomicron-mediated lipid transport, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPAR signaling pathway, organism-specific biosystem
• Function: apolipoprotein receptor binding; cholesterol binding; contributes_to cholesterol transporter activity; high-density lipoprotein particle binding; high-density lipoprotein particle receptor binding; lipase inhibitor activity; lipid binding; lipid transporter activity; phosphatidylcholine binding; phosphatidylcholine-sterol O-acyltransferase activator activity; phospholipid binding; protein binding; protein heterodimerization activity; protein homodimerization activity