Recombinant Mouse ASK1, His-tagged, T7 tagged
Cat.No. : | ASK1-3585M |
Product Overview : | Apoptosis Signal Regulating Kinase 1 (ASK1) |
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Description : | About the Marker: Effective Size Range: 10kDa to 70kDa.Protein bands: 10kDa, 14kDa, 18kDa, 22kDa, 26kDa, 33kDa, 44kDa and70kDa.Double intensity bands: The 26kDa, 18kDa, 10kDa bands are at doubleintensity to make location and size approximation of proteins of interestquick and easy.Ready-to-use: No need to heat, dilute or add reducing agents before use. |
Source : | E. Coli |
Species : | Mouse |
Tag : | His,T7 |
Form : | Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Molecular Mass : | 30.8kDa |
Protein length : | 1380 |
Endotoxin : | <1.0eu per 1ug (determined by the lal</1.0eu |
Purity : | >95% |
Applications : | SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP) |
Notes : | Small volumes of ASK1 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name : | Map3k5 mitogen-activated protein kinase kinase kinase 5 [ Mus musculus ] |
Official Symbol : | Map3k5 |
Synonyms : | ASK; ASK1; Mekk5; MAPKKK5; 7420452D20Rik; mitogen-activated protein kinase kinase kinase 5; ASK-1; MEKK 5; MEK kinase 5; MAPK/ERK kinase kinase 5; apoptosis signal-regulating kinase 1; mitogen activated protein kinase kinase kinase 5 |
Gene ID : | 26408 |
mRNA Refseq : | NM_008580 |
Protein Refseq : | NP_032606 |
UniProt ID : | O35099 |
Chromosome Location : | 10 A3; 10 |
Pathway : | Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Cellular Senescence, organism-specific biosystem |
Function : | ATP binding; cysteine-type endopeptidase activator activity involved in apoptotic process |
Products Types
◆ Recombinant Protein | ||
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MAP3K5-1093H | Recombinant Human MAP3K5 Protein (M649-K946), GST/His tagged | +Inquiry |
MAP3K5-1359H | Recombinant Human MAP3K5 Protein, His (Fc)-Avi-tagged | +Inquiry |
Map3k5-3931M | Recombinant Mouse Map3k5 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
MAP3K5-4504HCL | Recombinant Human MAP3K5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMAP3K5 has been implicated in various diseases, including neurodegenerative disorders, cardiovascular diseases, and inflammatory conditions.
Aberrant regulation of MAP3K5 has been associated with cancer development, as it can influence cell survival and death pathways.
MAP3K5 expression levels and activity may serve as biomarkers for specific diseases, providing valuable information for diagnosis and prognosis.
Research suggests that targeting MAP3K5 could have therapeutic implications in cancer treatment, potentially through the modulation of apoptosis in cancer cells.
Investigational studies and clinical trials are underway to explore the efficacy of MAP3K5 inhibitors in different disease contexts, including cancer.
Customer Reviews (3)
Write a reviewThe MAP3K5 protein has proven to be invaluable in protein electron microscopy structure analysis.
Its ability to provide accurate and reliable results in this particular application makes it a preferred choice for researchers studying antigen-antibody interactions and immune responses.
The MAP3K5 protein's sensitivity and specificity ensure precise measurements, contributing to the overall success of ELISA experiments.
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