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Recombinant Human AGFG2, His-tagged

Cat.No. : AGFG2-3613H
Product Overview : Arf-GAP domain and FG repeat-containing protein 2 (AGFG2)
  • Specification
  • Gene Information
  • Related Products
Description : This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. The 3" UTR of this gene contains an insulin receptor substrate 3-like pseudogene.
Source : E. Coli or Yeast
Species : Human
Tag : His
Form : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Protein length : 481
Purity : >90%
Notes : Small volumes of AGFG2 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage : Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Storage Buffer : PBS pH 7.4, 50% glycerol
Warning : This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name : AGFG2 ArfGAP with FG repeats 2 [ Homo sapiens ]
Official Symbol : AGFG2
Synonyms : AGFG2; ArfGAP with FG repeats 2; HIV 1 Rev binding protein like , HRBL; arf-GAP domain and FG repeat-containing protein 2; RABR; nucleoporin; HIV-1 Rev-binding protein-like protein; Rev/Rex activation domain binding protein-related; rev/Rex activation domain-binding protein related; arf-GAP domain and FG repeats-containing protein 2; HRBL;
Gene ID : 3268
mRNA Refseq : NM_006076
Protein Refseq : NP_006067
MIM : 604019
UniProt ID : O95081
Chromosome Location : 7q22.1
Function : ARF GTPase activator activity; metal ion binding; molecular_function; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (20)

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Is AGFG2 involved in the orchestration of protein sorting? 09/07/2021

AGFG2 deftly manages the sorting of proteins, ensuring their proper distribution within the cellular realm.

How does AGFG2 exert influence on endosomal transport? 07/28/2021

AGFG2's role extends to guiding the movement of cargo within the intricate networks of endosomal trafficking.

Are there ramifications for diseases involving AGFG2? 10/02/2020

AGFG2's tasks could interlink with conditions arising from disruptions in intracellular trafficking.

How might AGFG2's pursuits intersect with autophagy pathways? 05/11/2020

AGFG2's sphere of influence could potentially intermingle with the pathways regulating autophagy.

Is AGFG2 instrumental in the process of vesicle budding? 05/20/2019

AGFG2 is a central player in the art of vesicle budding and the strategic packaging of cargo for its cellular journey.

Can AGFG2 wield influence over membrane dynamics? 10/20/2018

Absolutely, AGFG2's impact extends to shaping membrane dynamics and orchestrating intracellular trafficking pathways.

Is AGFG2 a subject of continuous investigation? 10/04/2018

Yes, ongoing research continues to peel back the layers of AGFG2's diverse roles and potential impacts.

Can AGFG2 be a maestro orchestrating cell signaling pathways? 07/24/2018

AGFG2's potential influence extends to orchestrating the harmony of cell signaling pathways through membrane trafficking.

Can AGFG2's intricate functions be harnessed to illuminate cancer progression? 07/22/2018

Research endeavors delve into whether AGFG2's roles offer insights into the intricate dance of cancer progression.

In the grand scheme, how does AGFG2 contribute to cellular stress responses? 07/07/2018

AGFG2's multifaceted contributions shape cellular responses to an array of stressors and challenges.

What role does AGFG2 assume in the realm of Golgi apparatus? 06/01/2018

AGFG2 plays a pivotal part in upholding Golgi structure and facilitating the fluidity of vesicle trafficking within Golgi compartments.

How is AGFG2's structure characterized? 05/22/2018

AGFG2 boasts a unique protein architecture that's integral to its cellular functions.

Does AGFG2 wield influence over clathrin-coated vesicles? 12/31/2017

Absolutely, AGFG2 is a key contributor to the assembly and movement of clathrin-coated vesicles.

What part does AGFG2 play in the transportation of vesicles? 12/17/2017

AGFG2 assumes responsibility for vesicle trafficking, regulating the movement of cellular cargo.

In what way does AGFG2 contribute to the choreography of cellular secretion? 12/09/2017

AGFG2's active participation in vesicle transport directly impacts and propels cellular secretion processes.

What defines the AGFG2 protein? 06/09/2017

AGFG2, short for "Arf-GAP with FG repeats 2," operates in the realm of intracellular trafficking.

Are the threads of AGFG2 intertwined with neurodegenerative diseases? 03/04/2017

AGFG2's role undergoes scrutiny to determine its potential involvement in the realm of neurodegeneration.

How does AGFG2 contribute to the harmonious organization of organelles? 01/06/2017

AGFG2 assumes a pivotal role in ensuring the harmonious arrangement of organelles by guiding membrane trafficking.

How is AGFG2 scrutinized in research? 08/09/2016

Research endeavors to dissect AGFG2's roles, interactions, and possible contributions to cellular machinery.

Can AGFG2's prowess extend to restoring equilibrium within cells? 04/10/2016

Indeed, AGFG2's mastery of membrane trafficking aids in preserving cellular equilibrium and harmony.

Customer Reviews (5)

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Reviews
11/06/2021

    The product consistently demonstrated its efficacy by producing reliable and repeatable outcomes.

    10/13/2021

      The potent effects of the product enhanced our understanding of cellular processes.

      03/10/2020

        The insights gained from the product’s application justified its cost and marked a valuable investment.

        03/21/2019

          Protein AGFG2 consistently activated target genes, yielding reliable results.

          10/03/2017

            The product’s remarkable purity facilitated accurate quantification, minimizing data variability.

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