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Recombinant Human ABCA8, His-tagged

Cat.No. : ABCA8-3730H
Product Overview : ATP-binding cassette sub-family A member 8 (ABCA8), partial
  • Specification
  • Gene Information
  • Related Products
Description : The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The function of this protein has not yet been determined.
Source : E. Coli or Yeast
Species : Human
Tag : His
Form : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Protein length : 1581
Purity : >90%
Notes : Small volumes of ABCA8 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage : Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Storage Buffer : PBS pH 7.4, 50% glycerol
Warning : This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name : ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 [ Homo sapiens ]
Official Symbol : ABCA8
Synonyms : ABCA8; ATP-binding cassette, sub-family A (ABC1), member 8; ATP-binding cassette sub-family A member 8; KIAA0822; MGC163152;
Gene ID : 10351
mRNA Refseq : NM_007168
Protein Refseq : NP_009099
MIM : 612505
UniProt ID : O94911
Chromosome Location : 17q24
Pathway : ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem;
Function : ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; nucleotide binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What is the purity of these ABCA8 products? 04/14/2023

The purity of each products is different, you can check it on the product details page.

How does ABCA8 affect α-synuclein and p25α? 04/14/2023

Overexpression of ABCA8 in oligodendrocytes caused significant increases in both α-syn and p25α expression. 

Is it related to cancer prognosis? 04/14/2023

Gene product is not prognostic.

Will ABCA8 interact with ABCA1? 04/14/2023

It will. This interaction potentiates cholesterol efflux.

Which pathways are related to ABCA8? 04/14/2023

Among its related pathways are regulation of activated PAK-2p34 by proteasome mediated degradation and transport of inorganic cations/anions and amino acids/oligopeptides.

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08/02/2018

    Creative Biomart's after-sales service is very thoughtful and systematic, which makes me feel at ease.

    09/14/2017

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