"ABCD4" Related Products

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Recombinant Human ABCD4, His-tagged

Cat.No.: ABCD4-3739H
Product Overview: ATP-binding cassette sub-family D member 4 (ABCD4)
Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.
Source: E. Coli or Yeast
Species: Human
Tag: His
Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Protein length: 606
Purity: >90%
Notes: Small volumes of ABCD4 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Storage Buffer: PBS pH 7.4, 50% glycerol
Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name: ABCD4
Official Symbol: ABCD4
Synonyms: Recombinant ATP-binding cassette sub-fam...
Gene ID: 5826
mRNA Refseq: NM_005050.3
Protein Refseq: NP_005041.1
MIM: 603214
UniProt ID: O14678
Chromosome Location: Chromosome: 14; NC_000014.8 (74751980..74769767, complement). Location: 14q24.3
Function: ?it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype

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