Recombinant Human RECQL, His-tagged

• Cat.No.: RECQL-3746H
• Product Overview: ATP-dependent DNA helicase Q1 (RECQL)

Specification

• Description: The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5" and 3" UTRs, have been described.
• Source: E. Coli or Yeast
• Species: Human
• Tag: His
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Protein length: 649
• Purity: >90%
• Notes: Small volumes of RECQL recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: RECQL RecQ protein-like (DNA helicase Q1-like) [ Homo sapiens ]
• Official Symbol: RECQL
• Synonyms: RECQL; RecQ protein-like (DNA helicase Q1-like); ATP-dependent DNA helicase Q1; RecQ1; RecQL1; recQ protein-like 1; DNA-dependent ATPase Q1; DNA helicase, RecQ-like type 1; RECQL1
• Gene ID: 5965
• mRNA Refseq: NM_002907
• Protein Refseq: NP_002898
• MIM: 600537
• UniProt ID: P46063
• Chromosome Location: 12p12.1
• Function: ATP binding; ATP-dependent 3-5 DNA helicase activity; ATP-dependent DNA helicase activity; DNA binding; DNA helicase activity; DNA strand annealing activity; hydrolase activity; nucleotide binding; protein binding