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Recombinant Human ANP, His-tagged, GST-tagged

Cat.No. : ANP-3768H
Product Overview : Atrial Natriuretic Peptide (ANP)
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6.
Source : E. Coli
Species : Human
Tag : His,GST
Form : Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Molecular Mass : 42.7kDa
Protein length : 151
Endotoxin : <1.0eu per 1ug (determined by the lal</1.0eu
Purity : >95%
Applications : SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
Notes : Small volumes of ANP recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Warning : This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name : ANP
Official Symbol : ANP
Synonyms : NPPA; NPPA; ANF; ANP; PND; ATFB6; CDD-AN...
Gene ID : 4878
mRNA Refseq : NM_006172.3
Protein Refseq : NP_006163.1
MIM : 108780
UniProt ID : P01160
Chromosome Location : Chromosome: 1; NC_000001.10 (11905766..11907840, complement). Location: 1p36.21
Function : in cardiovascular homeostasis through regulation of natriuresis, diuresis,and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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