||Mouse B7-H2 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
||B7-H2, also known as CD275, is a member of the B7 family and has a predicted molecular weight of ~31 kDa. Mouse B7-H2 is expressed by antigen presenting cells including B cells, monocytes/macrophages and dendritic cells. It binds to the ICOS molecule. The interaction of ICOS/B7-H2 plays an important role in the T cell costimulation pathway.
||ETEVGAMVGS NVVLSCIDPH RRHFNLSGLY VYWQIENPEV SVTYYLPYKS PGINVDSSYK NRGHLSLDSM KQGNFSLYLK NVTPQDTQEF TCRVFMNTAT ELVKILEEVV RLRVAANFST PVISTSDSSN PGQERTYTCM SKNGYPEPNL YWINTTDNSL IDTALQNNTV YLNKLGLYDV ISTLRLPWTS HGDVLCCVEN VALHQNITSI SQAESFTGNN TKNPQETHNN ELKVLVPVLA VLAAAAFVSF IIYRRTRPHR SYTGPKTVQL ELTDHA (276)
||The Mouse B7-H2 protein can be used in cell culture, as an B7-H2 ELISA Standard, and as a Western Blot Control.