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Recombinant Chicken IL-8 (CXCL8)

Cat.No. : IL8-64C
Product Overview : Chicken IL-8 was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified.
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  • Gene Information
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Description : Interleukin-8 (IL-8), also known as CXCL8, is a CXC family member chemokine produced by macrophages and other cell types such as epithelial cells. There have been 17 different CXC chemokines described in mammals, that are subdivided into two categories, those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the CXC motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive CXC chemokines such as IL-8 specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2.
Source : Yeast
Species : Chicken
Form : Lyophilized
Molecular Mass : 9.5 kDa
AA Sequence : ALSQGRTLVK MGNELRCQCI STHSKFIHPK SIQDVKLTPS GPHCKNVEII ATLKDGREVC LDPTAPWVQL IVKALMAKAQ LNSDAPL (87)
Applications : The Chicken IL-8 protein can be used in cell culture, as an IL-8 ELISA Standard, and as a Western Blot Control.
Storage : -20 C

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the role of IL8 in the immune system? 08/31/2021

Acts as a chemical messenger in the immune system that regulates inflammation and attracts immune cells such as white blood cells.

How about the effect of IL8 on tumor? 06/01/2020

Regulating tumor microenvironment, promoting tumor growth and metastasis, and can be used in tumor therapy research.

What is the relationship between IL8 and inflammatory response? 01/18/2020

IL8 plays a role in regulating and promoting the migration and activation of inflammatory cells in the inflammatory response.

Which diseases can be treated with IL8? 12/02/2019

Can be used to treat inflammatory diseases (such as rheumatoid arthritis, psoriasis), tumors (such as lung cancer, breast cancer) and other diseases.

Is IL8 relevant to immunotherapy? 03/18/2019

Yes, IL8 is closely related to immunotherapy, which can enhance the role of the immune system and assist in the treatment of certain diseases.

By what method is IL8 generally prepared? 02/03/2019

IL8 is generally prepared by gene recombination technology, and the IL8 gene is introduced into the appropriate expression system, and then expressed and purified.

Customer Reviews (3)

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Reviews
10/28/2022

    IL8 has good fluorescence and absorption properties.

    11/29/2020

      NIPBL has good stability in different environments and is not easy to degrade.

      04/17/2019

        Through animal models or in vitro experiments to evaluate the mechanism of the recombinant protein in related diseases, we found that the effect is very good.

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