"BTN3A1" Related Products

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Recombinant Human BTN3A1, HIgG1 Fc-tagged

Cat.No.: BTN3A1-002H
Product Overview: The extracellular domain of human CD277 (AAI21801.1)(Gln30-Gly254) is fused to the N-terminus of the Fc region of human IgG1was expressed in CHO cell
Description: The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each
Source: CHO cells
Species: Human
Tag: HIgG1 Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Play a role in T-cell activation and in the adaptive immune response.
Molecular Mass: 50KDa (monomer)
AA Sequence: Gln30-Gly254
Endotoxin: <0.06 eu/μg as determined by lal test.>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: BTN3A1 butyrophilin, subfamily 3, member A1 [ Homo sapiens ]
Official Symbol: BTN3A1
Synonyms: BTN3A1; butyrophilin, subfamily 3, member A1; butyrophilin subfamily 3 member A1; BT3.1; BTF5; CD277; dJ45P21.3 (butyrophilin, subfamily 3, member A1); MGC141880;
Gene ID: 11119
mRNA Refseq: NM_001145008
Protein Refseq: NP_001138480
MIM: 613593
UniProt ID: O00481
Chromosome Location: 6p22.1
Function: protein binding;

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