Active Recombinant Mouse Pdcd1lg2, MIgG2a Fc-tagged

• Cat.No.: Pdcd1lg2-112M
• Product Overview: The extracellular domain of mouse CD273 [PD-L2] (NP_067371.1) (Leu20 -Arg219) is fused to the N-terminus of the Fc region of mouse IgG2a.

Specification

• Source: CHO cells
• Species: Mouse
• Tag: MIgG2a Fc-tagged
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated mouse T cells.
• Molecular Mass: 49KDa (monomer)
• AA Sequence: Leu20 -Arg219
• Endotoxin: <0.06 eu/μg as determined by lal test.>
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Pdcd1lg2 programmed cell death 1 ligand 2 [ Mus musculus ]
• Official Symbol: Pdcd1lg2
• Synonyms: PDCD1LG2; programmed cell death 1 ligand 2; PD-1 ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; butyrophilin-like protein; programmed death ligand 2; Btdc; B7-DC; PD-L2; F730015O22Rik; MGC124039; MGC124040
• Gene ID: 58205
• mRNA Refseq: NM_021396
• Protein Refseq: NP_067371
• Pathway: Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; PD-1 signaling, organism-specific biosystem
• Function: protein binding; receptor activity