"CD274" Related Products

Recombinant Mouse Interleukin CD274, MIgG2a Fc-tagged, mutant

Cat.No.: CD274-189M
Product Overview: The extracellular domain of mouse CD274 [B7-H1] (NP_068693.1) (Phe19-Arg237) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a was expressed in CHO cell.
Description: CD274 (CD274 molecule) is a protein-coding gene. Diseases associated with CD274 include pulmonary venoocclusive disease, and htlv-1 associated myelopathy/tropical spastic paraparesis, and among its related super-pathways are Immune System and Phosphorylation of CD3 and TCR zeta chains. GO annotations related to this gene include protein binding
Source: CHO cells
Species: Mouse
Tag: MIgG2a Fc-tagged, mutant
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated mouse T cells.
Molecular Mass: 53 KDa
AA Sequence: Phe19-Arg237
Endotoxin: <0.06 eu/μg as determined by lal test.>
Purity: ≥98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: Cd274 CD274 antigen [ Mus musculus ]
Official Symbol: CD274
Synonyms: CD274; CD274 antigen; programmed cell death 1 ligand 1; B7 homolog 1; PDCD1 ligand 1; programmed death ligand 1; B7h1; Pdl1; Pdcd1l1; Pdcd1lg1; A530045L16Rik;
Gene ID: 60533
mRNA Refseq: NM_021893
Protein Refseq: NP_068693
Pathway: Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; PD-1 signaling, organism-specific biosystem;
Function: protein binding; receptor activity;

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