|Official Full Name||CD274 CD274 molecule|
|Background||PD-L1, also known as CD274, B7-H1, is a 40 kD type I transmembrane protein member of B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-gamma activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production.|
|Synonyms||CD274; CD274 molecule; CD274 antigen , PDCD1LG1, programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; B7 homolog 1; B7 H; B7 H1; B7H1; PD L1; PDL1; CD274 antigen; PDCD1 ligand 1; programmed death ligand 1; B7-H; PD-L1; PDCD1L1; PDCD1LG1; MGC142294; MGC142296;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
cd274 involved in several pathways and played different roles in them. We selected most pathways cd274 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with cd274 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cell adhesion molecules (CAMs)||CD40LG; CD86; PVRL1B; CLDN8; SELPLG; NRXN3; ITGA6; Itgam&Itgb2; NCAM1B; OCLNB|
cd274 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cd274 itself. We selected most functions cd274 had, and list some proteins which have the same functions with cd274. You can find most of the proteins on our site.
|protein binding||STX16; FAM115A; GAN; PKD2L1; NUDT2; PTCH1; MTRR; FAM69A; OTOF; FGFBP1|
cd274 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cd274 here. Most of them are supplied by our site. Hope this information will be useful for your research of cd274.