"BMP2" Related Products

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Recombinant Human BMP2, HIgG1 Fc-tagged, mutant

Cat.No.: BMP2-56H
Product Overview: The extracellular domain of human BMP-2 (NP_001191.1) (Arg289-Arg396) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell.
Description: The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation
Source: CHO cells
Species: Human
Tag: HIgG1 Fc-tagged, mutant
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells.
Molecular Mass: 42 KDa (monomer)
AA Sequence: Arg289-Arg396
Endotoxin: <0.06 eu/μg as determined by lal>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: BMP2 bone morphogenetic protein 2 [ Homo sapiens ]
Official Symbol: BMP2
Synonyms: BMP2; bone morphogenetic protein 2; BMP2A; BMP-2A; bone morphogenetic protein 2A; BDA2;
Gene ID: 650
mRNA Refseq: NM_001200
Protein Refseq: NP_001191
MIM: 112261
UniProt ID: P12643
Chromosome Location: 20p12
Pathway: Adipogenesis, organism-specific biosystem; BMP Signalling Pathway, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Heart Development, organism-specific biosystem;
Function: BMP receptor binding; SMAD binding; activin receptor activity, type II; cytokine activity; growth factor activity; phosphatase activator activity; protein binding; protein domain specific binding; protein heterodimerization activity; protein homodimerizat

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