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Recombinant Mouse Bmp6

Cat.No.: Bmp6-28M
Product Overview: Recombinant Mouse Bmp6(Ser372-His510) was expressed in CHO Cells.
Description: Bone morphogenetic protein 6 is a protein that in humans is encoded by the BMP6 gene. The protein encoded by this gene is a member of the TGFβ superfamily. Bone morphogenetic proteins are known for their ability to induce the growth of bone and cartilage. BMP6 is able to induce all osteogenic markers in mesenchymal stem cells.
Source: CHO Cells
Species: Mouse
Predicted N Terminal: Ser372
Form: Disulfide-linked homodimer. Lyophilized from a 0.2 μm filtered solution in HCl.
Bio-activity: Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is typically 0.1 - 0.4 μg/mL.
Molecular Mass: Predicted Molecular Mass: 15.5 kDaSDS-PAGE: 18 kDa, reducing conditions
Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 °C as supplied.1 month, 2 to 8 °C under sterile conditions after reconstitution.3 months, -20 to -70 °C under sterile conditions after reconstitution.
Reconstitution: Reconstitute at 200 μg/mL in 4mM HCl.
Gene Name: Bmp6 bone morphogenetic protein 6 [ Mus musculus (house mouse) ]
Official Symbol: Bmp6
Synonyms: Bmp6; Vgr1; D13Wsu115e; bone morphogenetic protein 6; BMP-6; VG-1-related protein
Gene ID: 12161
mRNA Refseq: NM_007556
Protein Refseq: NP_031582
UniProt ID: P20722
Chromosome Location: 13 A3.3; 13 18.15 cM
Pathway: Endochondral Ossification; Hippo signaling pathway; Ovarian steroidogenesis
Function: BMP receptor binding; cytokine activity; growth factor activity

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