Native Human Cancer Antigen 72-4


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Native Human Cancer Antigen 72-4

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Cat.No. : CA 72-4-379H
Product Overview : Native Human CA 72-4 was purified from Human Metastatic Liver Carcinoma.
Description : Tumor-associated glycoprotein 72 (TAG-72) is a glycoprotein found on the surface of many cancer cells, including ovary, breast, colon, and pancreatic cells. It is a mucin-like molecule with a molar mass of over 1000 kDa. TAG-72 is a tumor marker and can be measured with radioimmunoassays like CA 72-4, which uses indium (111In) satumomab pendetide and iodine (125I) CC49 monoclonal antibody. This assay has a good specificity for gastric cancer, with a correlation to the neoplasia"s extension. It is used to identify relapses of the disease and to follow up the treatment.TAG-72 is also the target of the anti-cancer drugs anatumomab mafenatox and minretumomab.
Source : Human Metastatic Liver Carcinoma
Species : Human
Form : Clear and colorless. Liquid in PBS buffer, sucrose, pH 7.4.
Bio-activity : >100 kU/mL
Purity : >90% (SDS-PAGE)
Storage : Store at -20°C, Avoid repeated freeze thaw cycles.
Preservative : 0.05% Sodium Azide

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