GCSF Purification Resin

• Cat.No.: GCSF-001A
• Product Overview: GCSF Purification resin is an affinity medium specifically designed for the purification of G-CSF targets from recombinant feed streams.

Specification

• Cat.no: GCSF-001A
• Characteristics: G-CSF (granulocyte-colony stimulating factor) is a hormone stimulating the bone marrow to produce more white blood cells. The features are below:1. Rigid agarose base matrix allows high flow rates and processing of large sample volumes for increased throughput2. Non-mammalian derived product reduces regulatory concerns in the production of G-CSF for clinical applications
• Size: 25 mL, 200 mL, 1L
• Matrix: Highly cross-linked high-flow agarose
• Average particle size: 75 μm
• Ligand: Recombinant protein (Mr 14 400), produced in S. cerevisiae, with affinity for the protein G-CSF
• Ligand concentration: Approx. 7,5 mg/ml of medium
• Dynamic binding capacity: Approx. 3.9 mg G-CSF/mL medium
• Recommended flow rate: 600 cm/h
• Chemical stability: The affinity ligand is immobilized on the agarose base matrix via stable amide bonds. Stable in commonly used aqueous buffers.
• pH working range: 3-10
• pH CIP range: 2-12
• Temperature Stability: 4°C to 30°C