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Recombinant Human TACR1 293 Cell Lysate

Cat.No. : TACR1-1283HCL
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  • Gene Information
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Description : Antigen standard for tachykinin receptor 1 (TACR1), transcript variant short is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
Source : HEK 293 cells
Species : Human
Components : This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
Size : 0.1 mg
Storage Instruction : Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
Applications : ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.
Gene Name : TACR1 tachykinin receptor 1 [ Homo sapiens ]
Official Symbol : TACR1
Synonyms : TACR1; tachykinin receptor 1; TAC1R; substance-P receptor; NK1R; NKIR; SPR; NK-1R; NK-1 receptor; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor);
Gene ID : 6869
mRNA Refseq : NM_001058
Protein Refseq : NP_001049
MIM : 162323
UniProt ID : P25103
Chromosome Location : 2p13.1-p12
Pathway : Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Measles, organism-specific biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Is TACR1 protein a potential target for personalized pain management? 04/30/2021

Yes, understanding individual variations in TACR1 protein may lead to personalized approaches for pain management.

In what conditions is TACR1 protein dysregulation implicated? 09/14/2020

Dysregulation of TACR1 protein is implicated in chronic pain conditions such as fibromyalgia, migraine, and neuropathic pain.

Are there any current drugs that target TACR1 protein? 03/23/2020

Yes, drugs targeting TACR1 protein, such as NK1 receptor antagonists, are being investigated for their potential in managing pain.

Can genetic variations in TACR1 protein influence pain sensitivity? 01/06/2019

Yes, genetic variations in TACR1 protein have been associated with differences in pain sensitivity and susceptibility to chronic pain conditions.

Are there any side effects associated with targeting TACR1 protein for pain management? 05/19/2016

Side effects of targeting TACR1 protein may include nausea, vomiting, and potential effects on mood and emotional state.

Customer Reviews (3)

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Reviews
04/01/2022

    This level of support instills trust and confidence in the product, facilitating smooth and successful experimentation.

    04/23/2020

      The TACR1 protein comes highly recommended for a variety of research applications.

      08/12/2019

        Its exceptional performance in ELISA assays makes it a reliable tool for detecting and quantifying specific target molecules with high sensitivity and specificity.

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