Recombinant Human ADAT1, T7-tagged

• Cat.No.: ADAT1-28H
• Product Overview: Recombinant Human Adenosine Deaminase tRNA-Specific 1 produced inE.Coliis a non-glycosylated, polypeptide chain containing amino acids 1-502 and having a total molecular mass of 57.7 kda. ADAT-1 contains T7 tag at N-terminus. ADAT1 is purified by proprietary chromatographic techniques.

Specification

• Cat. No.: ADAT1-28H
• Description: This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA.
• Source: Escherichia Coli.
• Physical Appearance: Sterile Filtered clear solution.
• Purity: Greater than 95.0% as determined by SDS-PAGE.
• Formulation: Adenosine Deaminase tRNA-Specific-1 at 0.1 mg/ml, 10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3.
• Applications: • ELISA • MS • Inhibition Assays • Western Blotting.
• Stability: ADAT-1 although stable at 14°C for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Gene Information

• Gene Name: ADAT1 adenosine deaminase, tRNA-specific 1 [ Homo sapiens ]
• Synonyms: ADAT1; adenosine deaminase, tRNA-specific 1; HADAT1;tRNA-specific adenosine deaminase 1;hADAT1; tRNA-specific adenosine-37 deaminase; EC 3.5.4; adenosine deaminase acting on Trna; adenosine deaminase, tRNA-specific 1
• Gene ID: 23536
• mRNA Refseq: NM_012091
• Protein Refseq: NP_036223
• UniProt ID: Q9BUB4
• Chromosome Location: 16q23.1
• MIM: 604230
• Function: RNA binding; hydrolase activity; metal ion binding; tRNA-specific adenosine deaminase activity; zinc ion binding