Recombinant Human ACAN cell lysate

• Cat.No.: ACAN-35HCL

Specification

• Description: This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: ACAN aggrecan [ Homo sapiens ]
• Official Symbol: ACAN
• Synonyms: ACAN; aggrecan; AGC1, aggrecan 1 , chondroitin sulfate proteoglycan 1 , CSPG1, MSK16; aggrecan core protein; aggrecan proteoglycan; CSPGCP; large aggregating proteoglycan; cartilage-specific proteoglycan core protein; chondroitin sulfate proteoglycan core protein 1; AGC1; SEDK; AGCAN; CSPG1; MSK16
• Gene ID: 176
• mRNA Refseq: NM_001135
• Protein Refseq: NP_001126
• MIM: 155760
• UniProt ID: P16112
• Chromosome Location: 15q26.1
• Pathway: Endochondral Ossification, organism-specific biosystem
• Function: binding; extracellular matrix structural constituent; hyaluronic acid binding; protein binding; sugar binding