Recombinant Human ARHGEF6 cell lysate

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Recombinant Human ARHGEF6 cell lysate

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Cat.No. : ARHGEF6-119HCL
Description : Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 [ Homo sapiens ]
Official Symbol : ARHGEF6
Synonyms : ARHGEF6; Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6; mental retardation, X linked 46 , MRX46; rho guanine nucleotide exchange factor 6; alpha PIX; alphaPIX; Cool 2; Cool2; KIAA0006; PAK interacting exchange factor; alpha; Rac/Cdc42 guanine exchange factor (GEF) 6; PAK-interacting exchange factor alpha; PAK-interacting exchange factor, alpha; rac/Cdc42 guanine nucleotide exchange factor 6; PIXA; COOL2; MRX46; Cool-2; alpha-PIX;
Gene ID : 9459
mRNA Refseq : NM_004840
Protein Refseq : NP_004831
MIM : 300267
UniProt ID : Q15052
Chromosome Location : Xq26
Pathway : CDC42 signaling events, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-extracellular matrix interactions, organism-specific biosystem; Class I PI3K signaling events, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem;
Function : GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; protein binding;

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