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Recombinant Human ARMCX1 cell lysate

Cat.No. : ARMCX1-126HCL
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : ARMCX1 armadillo repeat containing, X-linked 1 [ Homo sapiens ]
Official Symbol : ARMCX1
Synonyms : ARMCX1; armadillo repeat containing, X-linked 1; armadillo repeat-containing X-linked protein 1; ALEX1; arm protein lost in epithelial cancers, X chromosome, 1; ARM protein lost in epithelial cancers on chromosome X 1; DKFZp686P06199;
Gene ID : 51309
mRNA Refseq : NM_016608
Protein Refseq : NP_057692
MIM : 300362
UniProt ID : Q9P291
Chromosome Location : Xq21.33-q22.2
Function : binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (23)

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Can changes in ARMCX1 expression levels affect cell proliferation or apoptosis? 11/23/2022

The impact of changes in ARMCX1 expression levels on cell proliferation or apoptosis is not currently clear. Further studies are needed to investigate whether alterations in ARMCX1 expression can influence these cellular processes.

Are there any known ARMCX1 gene polymorphisms associated with disease susceptibility? 11/15/2022

There is limited information available regarding ARMCX1 gene polymorphisms and their association with disease susceptibility. More research is required to determine any potential links between ARMCX1 polymorphisms and disease susceptibility.

Does the ARMCX1 protein have any known orthologs in other species? 11/06/2022

Yes, the ARMCX1 protein has orthologs in various species, including mammals such as mice, rats, and primates. These orthologs share high sequence similarity and are believed to have similar functions.

Is the expression of ARMCX1 protein tissue-specific? 07/27/2022

The expression pattern of the ARMCX1 protein across different tissues and organs varies. It is expressed in various tissues, including the brain, testes, heart, and placenta, suggesting its potential roles in multiple biological processes.

Can mutations in the ARMCX1 gene lead to loss or gain of protein function? 06/18/2022

Mutations in the ARMCX1 gene can potentially lead to loss or gain of protein function. Loss-of-function mutations may result in reduced or altered ARMCX1 protein activity, while gain-of-function mutations may enhance its activity or disrupt normal cellular processes.

Is the ARMCX1 protein involved in any signaling pathways? 02/15/2022

The involvement of the ARMCX1 protein in signaling pathways is not yet well characterized. However, studies suggest its potential interaction with other proteins involved in cellular signaling and gene expression regulation.

How is the ARMCX1 protein linked to intellectual disability? 11/13/2021

Mutations or genetic variations in the ARMCX1 gene have been identified in individuals with X-linked intellectual disability. These mutations are believed to disrupt normal neuronal development and synaptic function, leading to cognitive impairments.

Does the ARMCX1 protein have any known functional domains or motifs? 03/14/2021

Yes, the ARMCX1 protein contains multiple armadillo (ARM) repeat domains. Armadillo repeats are known for their protein-protein interaction properties, suggesting that ARMCX1 may interact with other proteins through these domains.

Can ARMCX1 expression levels be used as a biomarker for any diseases? 11/18/2020

At present, there are no established biomarkers based on ARMCX1 expression levels for any diseases. However, future research may reveal potential associations with specific diseases, leading to the identification of ARMCX1 as a biomarker candidate.

Is the expression of the ARMCX1 gene tissue-specific? 11/13/2020

There is evidence to suggest that the expression of the ARMCX1 gene is indeed tissue-specific. Studies have shown that ARMCX1 is expressed in a variety of tissues, including the brain, heart, kidney, and testis. However, the precise tissue-specific regulation of ARMCX1 expression is still not well understood.

Are there any animal models available for studying the function of ARMCX1? 07/14/2019

Currently, there are no specific animal models available for studying the function of ARMCX1. The generation of animal models, such as knockout mice, could be valuable for investigating the biological role of ARMCX1 in vivo.

Is there ongoing research on the ARMCX1 protein? 05/28/2019

Yes, scientists are actively studying the ARMCX1 protein to understand its function, mechanism of action, and its association with specific genetic disorders or conditions.

Is the ARMCX1 protein involved in any disease pathways or conditions apart from X-linked intellectual disability? 07/30/2018

Although primarily associated with X-linked intellectual disability, the ARMCX1 protein's potential involvement in other diseases or conditions is not yet well established. Further research is needed to explore its role in different biological contexts.

Are there any known drugs or treatments targeting the ARMCX1 protein? 07/02/2018

Currently, there are no specific drugs or treatments targeting the ARMCX1 protein. However, ongoing research may identify potential therapeutic interventions related to its functions and associated disorders in the future.

Is the ARMCX1 protein involved in any specific developmental processes? 04/15/2018

The ARMCX1 protein's role in developmental processes is not yet clearly defined. However, its expression in various organs and tissues suggests potential involvement in developmental events such as neurogenesis and organogenesis.

Are there any drugs or therapeutics targeting the ARMCX1 protein? 11/17/2017

Currently, there are no specific drugs or therapeutics targeting the ARMCX1 protein. However, further exploration of its function and involvement in diseases may provide opportunities for the development of targeted therapies in the future.

What subcellular localization does the ARMCX1 protein have? 09/17/2017

The ARMCX1 protein is predominantly localized in the cytoplasm of cells. However, it has been reported to shuttle between the cytoplasm and the nucleus, suggesting potential nuclear functions.

Are there any known interacting proteins of the ARMCX1 protein? 02/24/2017

Some proteins that have been reported to interact with the ARMCX1 protein include BRCA1-associated RING domain protein 1 (BARD1) and the histone deacetylase HDAC6. These interactions may contribute to the protein's functional role in cellular processes.

Does the ARMCX1 protein have any binding partners? 08/18/2016

The ARMCX1 protein has been shown to interact with various proteins, such as transcription factors, co-factors, and components of the chromatin remodeling complex. These interactions may be crucial for its function and role in cellular processes.

Is there any known role of ARMCX1 in cell signaling pathways? 07/06/2016

The exact role of ARMCX1 in cell signaling pathways is not well understood. However, studies have suggested potential involvement of ARMCX1 in pathways such as MAPK/ERK signaling and the Wnt/β-catenin pathway. Further investigation is needed to elucidate the precise mechanisms and functions of ARMCX1 in these pathways.

Has ARMCX1 been implicated in any other neurological disorders apart from intellectual disability? 06/24/2016

Currently, the main association of ARMCX1 is with X-linked intellectual disability. There is no strong evidence implicating it in other neurological disorders. However, its potential role in other disorders or neurological conditions remains a subject of ongoing research.

Are there any known genetic disorders or conditions associated with mutations in the ARMCX1 gene? 03/01/2016

Mutations in the ARMCX1 gene have been associated with X-linked intellectual disability, which is a condition characterized by developmental delays and intellectual impairments in affected individuals.

How is the ARMCX1 protein regulated in the cell? 01/12/2016

The regulation of ARMCX1 protein is not yet fully understood. However, studies suggest that its expression and activity can be regulated at the transcriptional level through various signaling pathways and transcription factors.

Customer Reviews (6)

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Reviews
01/27/2020

    the manufacturer's dedication to excellent technical support assures me that any challenges or obstacles I encounter will be swiftly resolved.

    05/03/2019

      ARMCX1 protein is highly recommended for researchers, as it demonstrates excellent performance in WB experiments and has proven useful in protein electron microscopy structure analysis.

      12/01/2018

        The high-quality ARMCX1 protein available from manufacturers ensures consistent and reproducible results in WB experiments, making it an essential tool for researchers studying ANO2-related pathways and biological processes.

        04/12/2018

          Its top-notch purity and integrity instill confidence in obtaining precise and reliable data, thereby enabling significant advancements in my research.

          12/07/2017

            Coupled with the manufacturer's commitment to impeccable technical support, I am equipped with the necessary tools to overcome any hurdles and achieve significant breakthroughs in my scientific pursuits.

            09/04/2016

              ARMCX1 protein is highly recommended for researchers due to its excellent performance in various assays, particularly in Western blotting (WB) experiments, and its applicability in protein electron microscopy structure analysis.

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