Recombinant Human CACNG7 cell lysate

• Cat.No.: CACNG7-271HCL

Specification

• Description: The mouse protein stargazin is one of five subunits comprising neuronal voltage-gated calcium channels. This subunit, gamma, is thought to stabilize the calcium channel in an inactive (closed) state. Mutations in the gene encoding stargazin have been associated with absence seizures, also known as petit-mal or spike-wave seizures. The protein encoded by this gene is structurally similar to the mouse stargazin protein and is a member of the neuronal calcium channel gamma subunit protein family. However, it appears unlikely that the encoded protein is part of a functional calcium channel. Rather, it appears to inhibit the expression of a specific calcium channel subunit.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: CACNG7 calcium channel, voltage-dependent, gamma subunit 7 [ Homo sapiens ]
• Official Symbol: CACNG7
• Synonyms: CACNG7; calcium channel, voltage-dependent, gamma subunit 7; voltage-dependent calcium channel gamma-7 subunit; TARP gamma-7; transmembrane AMPAR regulatory protein gamma-7; neuronal voltage-gated calcium channel gamma-7 subunit
• Gene ID: 59284
• mRNA Refseq: NM_031896
• Protein Refseq: NP_114102
• MIM: 606899
• UniProt ID: P62955
• Chromosome Location: 19q13.4
• Pathway: Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem
• Function: voltage-gated calcium channel activity; voltage-gated ion channel activity