Recombinant Human CALCR cell lysate

• Cat.No.: CALCR-272HCL

Specification

• Description: This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: CALCR calcitonin receptor [ Homo sapiens ]
• Official Symbol: CALCR
• Synonyms: CALCR; calcitonin receptor; CTR; CRT; CT-R; CTR1
• Gene ID: 799
• mRNA Refseq: NM_001164737
• Protein Refseq: NP_001158209
• MIM: 114131
• UniProt ID: P30988
• Chromosome Location: 7q21.3
• Pathway: Calcitonin-like ligand receptors, organism-specific biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem
• Function: calcitonin binding; NOT calcitonin binding; calcitonin binding; calcitonin receptor activity; calcitonin receptor activity; protein binding; protein transporter activity; receptor activity; receptor activity; signal transducer activity