Recombinant Human CALD1 cell lysate

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Recombinant Human CALD1 cell lysate

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Cat.No. : CALD1-274HCL
Description : This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : CALD1 caldesmon 1 [ Homo sapiens ]
Official Symbol : CALD1
Synonyms : CALD1; caldesmon 1; caldesmon; CDM; H CAD; L CAD; HCAD; LCAD; H-CAD; L-CAD; NAG22; MGC21352;
Gene ID : 800
mRNA Refseq : NM_033138
Protein Refseq : NP_149129
MIM : 114213
UniProt ID : Q05682
Chromosome Location : 7q33
Pathway : Muscle contraction, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; Smooth Muscle Contraction, organism-specific biosystem; Vascular smooth muscle contraction, organism-specific biosystem; Vascular smooth muscle contraction, conserved biosystem;
Function : actin binding; calmodulin binding; myosin binding; tropomyosin binding;

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