Recombinant Human CAPNS1 cell lysate

• Cat.No.: CAPNS1-279HCL

Specification

• Description: Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: CAPNS1 calpain, small subunit 1 [ Homo sapiens ]
• Official Symbol: CAPNS1
• Synonyms: CAPNS1; calpain, small subunit 1; CAPN4; calpain small subunit 1; 30K; CANP; CANPS; CDPS; CANP small subunit; calpain regulatory subunit; calpain, small polypeptide; calpain 4, small subunit (30K); calcium-dependent protease, small subunit; calcium-dependent protease small subunit 1; calcium-activated neutral proteinase small subunit; CSS1; CALPAIN4
• Gene ID: 826
• mRNA Refseq: NM_001003962
• Protein Refseq: NP_001003962
• MIM: 114170
• UniProt ID: P04632
• Chromosome Location: 19q13.1
• Pathway: Integrin-mediated cell adhesion, organism-specific biosystem
• Function: calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; protein binding; protein heterodimerization activity