Recombinant Human CARD14 cell lysate


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Recombinant Human CARD14 cell lysate

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Cat.No. : CARD14-282HCL
Description : The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : CARD14 caspase recruitment domain family, member 14 [ Homo sapiens ]
Official Symbol : CARD14
Synonyms : CARD14; caspase recruitment domain family, member 14; caspase recruitment domain-containing protein 14; BIMP2; CARMA2; carma 2; card-maguk protein 2; CARD-containing MAGUK protein 2; bcl10-interacting maguk protein 2; FLJ38097;
Gene ID : 79092
mRNA Refseq : NM_001257970
Protein Refseq : NP_001244899
MIM : 607211
UniProt ID : Q9BXL6
Chromosome Location : 17q25
Function : CARD domain binding;

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