Recombinant Human CARD8 cell lysate


Home / Products / Cell & Tissue Lysates / Over-Expression Lysates / Recombinant Human CARD8 cell lysate

Recombinant Human CARD8 cell lysate

CARD8 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : CARD8-283HCL
Description : The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : CARD8 caspase recruitment domain family, member 8 [ Homo sapiens ]
Official Symbol : CARD8
Synonyms : CARD8; caspase recruitment domain family, member 8; caspase recruitment domain-containing protein 8; CARDINAL; Dakar; KIAA0955; NDPP; TUCAN; apoptotic protein NDPP1; CARD inhibitor of NF-kappaB-activating ligands; tumor up-regulated CARD-containing antagonist of CASP9; tumor up-regulated CARD-containing antagonist of caspase nine; DACAR; DAKAR; NDPP1; FLJ18119; FLJ18121; MGC57162; DKFZp779L0366;
Gene ID : 22900
mRNA Refseq : NM_001184900
Protein Refseq : NP_001171829
MIM : 609051
UniProt ID : Q9Y2G2
Chromosome Location : 19q13.33
Pathway : NOD-like receptor signaling pathway, organism-specific biosystem; NOD-like receptor signaling pathway, conserved biosystem;
Function : NACHT domain binding; cysteine-type endopeptidase activator activity involved in apoptotic process; protein binding; protein homodimerization activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Online Inquiry

  • Note: There will be extra charge for optional service!
  • Verification Code Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy