Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human ADAP2 cell lysate

Cat.No. : ADAP2-336HCL
  • Specification
  • Gene Information
  • Related Products
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : ADAP2 ArfGAP with dual PH domains 2 [ Homo sapiens ]
Official Symbol : ADAP2
Synonyms : ADAP2; ArfGAP with dual PH domains 2; CENTA2, centaurin, alpha 2; arf-GAP with dual PH domain-containing protein 2; cnt-a2; centaurin beta; centaurin-alpha-2; centaurin, alpha 2; centaurin-alpha 2 protein; CENTA2; cent-b; HSA272195;
Gene ID : 55803
mRNA Refseq : NM_018404
Protein Refseq : NP_060874
MIM : 608635
UniProt ID : Q9NPF8
Chromosome Location : 17q11.2
Function : ARF GTPase activator activity; GTPase activator activity; inositol 1,3,4,5 tetrakisphosphate binding; metal ion binding; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding, bridging; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (13)

Ask a question
What research is currently being done on ADAP2 protein? 06/02/2022

Current research on ADAP2 protein is focused on understanding its role in various diseases, including cancer, hypertension, and neuropathic pain. Researchers are also investigating the molecular mechanisms underlying ADAP2 signaling pathways and identifying potential therapeutic targets for ADAP2-based therapies. Additionally, studies are ongoing to develop novel methods for detecting and measuring ADAP2 protein expression in clinical samples, which may have diagnostic and prognostic implications for various diseases.

What are some challenges associated with the development of ADAP2-based therapies? 01/01/2022

One challenge associated with the development of ADAP2-based therapies is the limited knowledge of its molecular function and signaling pathway in different diseases. Additionally, the use of ADAP2-based therapies may also be limited by issues related to specificity, toxicity, and dosing. Thus, further research is needed to better understand the role of ADAP2 in various diseases and to identify safe and effective ways to target ADAP2 for therapeutic purposes.

Can ADAP2 protein be used as a diagnostic marker for any diseases? 12/14/2021

There is currently no evidence to suggest that ADAP2 protein could be used as a diagnostic marker for any specific disease. However, research has shown that ADAP2 expression levels may be altered in certain diseases, such as cancer, suggesting that it may be a useful biomarker for disease progression or response to treatment. Further research is needed to determine the potential diagnostic role of ADAP2 in various diseases.

Are there any small molecule inhibitors or modulators of ADAP2 protein currently available? 10/11/2021

At present, there are no small molecule inhibitors or modulators of ADAP2 protein available. However, research is ongoing to identify and develop selective inhibitors or modulators of ADAP2 activity for therapeutic use in various diseases.

What are the potential applications of ADAP2 protein? 06/09/2020

The potential applications of ADAP2 protein include drug discovery and development, diagnostics, and targeted therapies for various diseases, such as cancer, neuropathic pain, and inflammatory disorders. ADAP2 is involved in several cellular signaling pathways, including T-cell activation, cell adhesion, and migration, and has been shown to be overexpressed in certain cancers. This makes ADAP2 a potential drug target for cancer therapy. ADAP2 is also involved in the regulation of neuropathic pain, and targeting ADAP2 signaling may provide a novel strategy for treating this condition. Moreover, ADAP2 may serve as a biomarker for some diseases, and its detection in body fluids or tissues may aid in diagnosis and prognosis.

How is ADAP2 protein used in targeted therapies? 09/06/2019

ADAP2 protein can be targeted for therapies aimed at specific diseases or conditions. For example, targeting ADAP2 with small molecule inhibitors or monoclonal antibodies may be effective in treating certain cancers or neuropathic pain. These therapies may work by selectively inhibiting ADAP2-mediated signaling pathways that contribute to disease development or progression. Development and optimization of ADAP2-targeted therapies can be facilitated by studies using ADAP2 protein in vitro and in vivo.

Are there any ongoing clinical trials involving ADAP2 protein as a therapeutic target? 06/06/2019

Currently, there are no clinical trials involving ADAP2 protein as a therapeutic target. However, there are preclinical studies investigating ADAP2-based therapies in various diseases, such as hypertension, neuropathic pain, and cancer.

How is ADAP2 protein used in drug discovery and development? 05/08/2019

ADAP2 protein can be used in drug discovery and development by serving as a target for small molecule inhibitors or monoclonal antibodies. These compounds can be designed to bind specifically to ADAP2 and block its function in various cellular signaling pathways. High-throughput screening methods can be used to identify lead compounds that show promising inhibition of ADAP2 activity. These compounds can then be optimized for potency, selectivity, and pharmacokinetic properties to develop potential drug candidates. Additionally, ADAP2 protein can be used in preclinical studies to evaluate the efficacy and safety of ADAP2-targeted therapies.

How might ADAP2 protein be used in combination with other therapies? 12/14/2018

ADAP2 protein may be used in combination with other therapies to enhance their efficacy or overcome resistance. For example, ADAP2 inhibitors may be used in combination with blood pressure-lowering drugs to improve their effectiveness in the treatment of hypertension. Additionally, ADAP2 may also be involved in the development of drug resistance in cancer cells, and targeting ADAP2 in combination with chemotherapy or other targeted therapies may improve their efficacy.

How is ADAP2 protein used in diagnostics? 10/19/2018

ADAP2 protein can be used as a biomarker for the diagnosis of certain diseases. For example, ADAP2 expression has been shown to be elevated in some cancers, such as breast, lung, and ovarian cancers. Detection of ADAP2 in tumor tissues or blood samples may therefore aid in the diagnosis and prognosis of these cancers. In addition, ADAP2 may be a biomarker for other diseases, such as inflammatory disorders or neuropathic pain. Development of immunoassays or other detection methods specific for ADAP2 may enable its use as a diagnostic tool.

What are some potential applications of ADAP2 protein in medicine? 04/27/2018

ADAP2 protein has potential applications in the treatment of various diseases, including cancer, neurological disorders, and cardiovascular diseases. For example, ADAP2 may play a role in the regulation of blood pressure and nerve function and may be targeted for the treatment of hypertension or neuropathic pain. Additionally, ADAP2 may also be involved in the development and progression of some cancers, and targeting ADAP2 may provide a novel therapeutic approach for cancer treatment.

Is there any commercial availability of ADAP2 protein or antibodies? 06/19/2015

Currently, there are no commercial sources of purified ADAP2 protein or antibodies available for purchase. However, researchers can obtain ADAP2 antibodies from custom antibody manufacturers and research supply companies. Researchers can also create their own ADAP2 antibodies using recombinant protein expression systems or through immunization of animals.

What is the mechanism of action of ADAP2 protein? 05/23/2015

The exact mechanism of action of ADAP2 protein is not well understood. However, it has been suggested that ADAP2 may play a role in regulating protein-protein interactions and signal transduction pathways in various cell types. ADAP2 has been shown to interact with several other proteins, including tyrosine kinases, cytoskeletal proteins, and transcription factors, which may be involved in downstream signaling pathways related to cell growth, differentiation, and migration.

Customer Reviews (0)

Write a review

Ask a Question for All ADAP2 Products

Required fields are marked with *

My Review for All ADAP2 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends