"COBRA1" Related Products

Recombinant Human COBRA1 cell lysate

Cat.No.: COBRA1-377HCL
Description: NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: COBRA1 cofactor of BRCA1 [ Homo sapiens ]
Official Symbol: COBRA1
Synonyms: COBRA1; cofactor of BRCA1; negative elongation factor B; KIAA1182; NELF B; negative elongation factor protein B; NELFB; NELF-B; RP13-122B23.3; DKFZp586B0519;
Gene ID: 25920
mRNA Refseq: NM_015456
Protein Refseq: NP_056271
MIM: 611180
UniProt ID: Q8WX92
Chromosome Location: 9q34
Pathway: Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; Disease, organism-specific biosystem; Formation of HIV-1 elongation complex containing HIV-1 Tat, organism-specific biosystem; Formation of HIV-1 elongation complex in the absence of HIV-1 Tat, organism-specific biosystem; Formation of RNA Pol II elongation complex, organism-specific biosystem; Formation of the Early Elongation Complex, organism-specific biosystem; Formation of the HIV-1 Early Elongation Complex, organism-specific biosystem;
Function: protein binding;
Products Types ◆ Recombinant Protein

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