Cat.No.: | DOCK2-503HCL |
Description: | The DOCK2 gene encodes a hematopoietic cell-specific CDM family protein that is indispensable for lymphocyte chemotaxis. |
Species: | Human |
Size: | 100 ul |
Storage Buffer: | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications: | Western Blot; |
Gene Name: | DOCK2 dedicator of cytokinesis 2 [ Homo sapiens ] |
Official Symbol: | DOCK2 |
Synonyms: | DOCK2; dedicator of cytokinesis 2; dedicator of cyto kinesis 2; dedicator of cytokinesis protein 2; KIAA0209; dedicator of cyto-kinesis 2; FLJ46592; |
Gene ID: | 1794 |
mRNA Refseq: | NM_004946 |
Protein Refseq: | NP_004937 |
MIM: | 603122 |
UniProt ID: | Q92608 |
Chromosome Location: | 5q35.1 |
Pathway: | Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Disease, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; HIV Infection, organism-specific biosystem; |
Function: | GTP binding; GTPase binding; Rac GTPase activator activity; Rac guanyl-nucleotide exchange factor activity; T cell receptor binding; electron carrier activity; guanyl-nucleotide exchange factor activity; heme binding; |
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