Recombinant Human DYNC1H1 cell lysate

• Cat.No.: DYNC1H1-519HCL

Specification

• Description: Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 [ Homo sapiens ]
• Official Symbol: DYNC1H1
• Synonyms: DYNC1H1; dynein, cytoplasmic 1, heavy chain 1; DNCH1, DNCL, DNECL, dynein, cytoplasmic, heavy polypeptide 1; cytoplasmic dynein 1 heavy chain 1; DHC1; Dnchc1; HL 3; p22; dynein heavy chain, cytosolic; cytoplasmic dynein heavy chain 1; dynein, cytoplasmic, heavy polypeptide 1; DNCL; DYHC; HL-3; CMT20; DHC1a; DNCH1; DNECL; MRD13; KIAA0325; DKFZp686P2245
• Gene ID: 1778
• mRNA Refseq: NM_001376
• Protein Refseq: NP_001367
• MIM: 600112
• UniProt ID: Q14204
• Chromosome Location: 14q32.31
• Pathway: Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; G2/M Transition, organism-specific biosystem; Lissencephaly gene (LIS1) in neuronal migration and development, organism-specific biosystem; Loss of Nlp from mitotic centrosomes, organism-specific biosystem; Loss of proteins required for interphase microtubule organization??from the centrosome, organism-specific biosystem
• Function: ATP binding; ATPase activity, coupled; microtubule motor activity; nucleotide binding; protein binding