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Recombinant Human E4F1 cell lysate

Cat.No. : E4F1-522HCL
  • Specification
  • Gene Information
  • Related Products
Description : The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence.
Species : Human
Size : 100 ul
Storage Buffer : 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications : Western Blot;
Gene Name : E4F1 E4F transcription factor 1 [ Homo sapiens ]
Official Symbol : E4F1
Synonyms : E4F1; E4F transcription factor 1; transcription factor E4F1; E4F; p50E4F; p120E4F; transcription factor E4F; putative E3 ubiquitin-protein ligase E4F1; MGC99614;
Gene ID : 1877
mRNA Refseq : NM_004424
Protein Refseq : NP_004415
MIM : 603022
UniProt ID : Q66K89
Chromosome Location : 16p13.3
Pathway : p53 pathway, organism-specific biosystem;
Function : DNA binding; cAMP response element binding; ligase activity; metal ion binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription corepressor activity; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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