Recombinant Human EIF2B2 cell lysate

• Cat.No.: EIF2B2-540HCL

Specification

• Species: Human
• Tag: Non
• Description: Eukaryotic initiation factor-2B (EIF2B) is a GTP exchange protein essential for protein synthesis. It consists of alpha (EIF2B1; MIM 606686), beta (EIF2B2), gamma (EIF2B3; MIM 606273), delta (EIF2B4; MIM 606687), and epsilon (EIF2B5; MIM 603945) subunits. EIF2B activates its EIF2 (see MIM 603907) substrate by exchanging EIF2-bound GDP for GTP.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa [ Homo sapiens ]
• Official Symbol: EIF2B2
• Synonyms: EIF2B2; eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; eukaryotic translation initiation factor 2B, subunit 2 (beta, 39kD); translation initiation factor eIF-2B subunit beta; EIF 2Bbeta; EIF2B; S20I15; S20III15; eIF-2B GDP-GTP exchange factor subunit beta; EIF-2Bbeta
• Gene ID: 8892
• mRNA Refseq: NM_014239
• Protein Refseq: NP_055054
• MIM: 606454
• UniProt ID: P49770
• Chromosome Location: 14q24.3
• Pathway: Cap-dependent Translation Initiation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Gene Expression, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Recycling of eIF2:GDP, organism-specific biosystem
• Function: ATP binding; GTP binding; contributes_to guanyl-nucleotide exchange factor activity; contributes_to guanyl-nucleotide exchange factor activity; protein binding; contributes_to translation initiation factor activity