Cat.No.: | EME1-552HCL |
Description: | This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability |
Species: | Human |
Size: | 100 ul |
Storage Buffer: | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications: | Western Blot; |
Gene Name: | EME1 essential meiotic endonuclease 1 homolog 1 (S. pombe) [ Homo sapiens ] |
Official Symbol: | EME1 |
Synonyms: | EME1; essential meiotic endonuclease 1 homolog 1 (S. pombe); crossover junction endonuclease EME1; FLJ31364; MMS4L; SLX2 structure specific endonuclease subunit homolog A (S. cerevisiae); SLX2A; hMMS4; MMS4 homolog; homolog of yeast EME1 endonuclease; essential meiotic endonuclease 1 homolog 2; SLX2 structure-specific endonuclease subunit homolog A; |
Gene ID: | 146956 |
mRNA Refseq: | NM_001166131 |
Protein Refseq: | NP_001159603 |
MIM: | 610885 |
UniProt ID: | Q96AY2 |
Chromosome Location: | 17q21.33 |
Pathway: | Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem; |
Function: | DNA binding; endonuclease activity; hydrolase activity; metal ion binding; protein binding; |
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