Recombinant Human EXO1 cell lysate

• Cat.No.: EXO1-580HCL

Specification

• Description: This gene encodes a protein with 5 to 3 exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: EXO1 exonuclease 1 [ Homo sapiens ]
• Official Symbol: EXO1
• Synonyms: EXO1; exonuclease 1; HEX1; hExoI; rad2 nuclease family member; homolog of S. cerevisiae exonuclease 1; hExo1; rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1
• Gene ID: 9156
• mRNA Refseq: NM_003686
• Protein Refseq: NP_003677
• MIM: 606063
• UniProt ID: Q9UQ84
• Chromosome Location: 1q42-q43
• Pathway: Mismatch repair, organism-specific biosystem; Mismatch repair, conserved biosystem
• Function: 5-3 exodeoxyribonuclease activity; 5-3 exonuclease activity; DNA binding; double-stranded DNA specific 5-3 exodeoxyribonuclease activity; endonuclease activity; exonuclease activity; exonuclease activity; flap endonuclease activity; metal ion binding; protein binding; ribonuclease H activity; single-stranded DNA specific 5-3 exodeoxyribonuclease activity; structure-specific DNA binding