"FANCM" Related Products

Recombinant Human FANCM cell lysate

Cat.No.: FANCM-595HCL
Description: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M.
Species: Human
Size: 100 ul
Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Applications: Western Blot;
Gene Name: FANCM Fanconi anemia, complementation group M [ Homo sapiens ]
Official Symbol: FANCM
Synonyms: FANCM; Fanconi anemia, complementation group M; KIAA1596; Fanconi anemia group M protein; FAAP250; protein Hef ortholog; ATP-dependent RNA helicase FANCM; fanconi anemia-associated polypeptide of 250 kDa; MGC176453;
Gene ID: 57697
mRNA Refseq: NM_020937
Protein Refseq: NP_065988
MIM: 609644
UniProt ID: Q8IYD8
Chromosome Location: 14q21.3
Pathway: DNA Repair, organism-specific biosystem; FA core complex, organism-specific biosystem; Fanconi Anemia pathway, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem;
Function: ATP binding; ATP-dependent helicase activity; DNA binding; chromatin binding; helicase activity; hydrolase activity; nuclease activity; nucleotide binding; protein binding;

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