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Recombinant Human FANCM Protein, GST-tagged

Cat.No. : FANCM-3835H
Product Overview : Human FANCM full-length ORF ( AAH36056.1, 1 a.a. - 669 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 102 kDa
AA Sequence : MSGRQRTLFQTWGSSISRSSGTPGC SSGTERPQSPGSSKAPLPAAAEAQL ESDDDVLLVAAYEAERQLCLENGGF CTSAGALWIYPTNCPVRDYQLHISR AALFCNTLVCLPTGLGKTFIAAVVM YNFYRWFPSGKVVFMAPTKPLVTQQ IEACYQVMGIPQSHMAEMTGSTQAS TRKEIWCSKRVLFLTPQVMVNDLSR GACPAAEIKCLVIDEAHKALGNYAY CQVVRELVKYTNHFRILALSATPGS DIKAVQQVITNLLIGQIELRSEDSP DILTYSHERKVEKLIVPLGEELAAI QKTYIQILESFARSLIQRNVLMRRD IPNLTKYQIILARDQFRKNPSPNIV GIQQGIIEGEFAICISLYHGYELLQ QMGMRSLYFFLCGIMDGTKGMTRSK NELGRNEDFMKLYNHLECMFARTRS TSANGISAIQQGDKNKKFVYSHPKL KKLEEVVIEHFKSWNAENTTEKKRD ETRVMIFSSFRDSVQEIAEMLSQHQ PIIRVMTFVGHASGKSTKGFTQKEQ LEVVKQFRDGGYNTLVSTCVGEEGL DIGEVDLIICFDSQKSPIRLVQRMG RTGRKRQGRIVIILSEGREERIYNQ SQSNKRSIYKAISSNRQVLHFYQRS PRMVPDGINPKLHKMFITHGVYEPE KPSRNLQRKSSIFSYRDGK
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : FANCM Fanconi anemia, complementation group M [ Homo sapiens ]
Official Symbol : FANCM
Synonyms : FANCM; Fanconi anemia, complementation group M; KIAA1596; Fanconi anemia group M protein; FAAP250; protein Hef ortholog; ATP-dependent RNA helicase FANCM; fanconi anemia-associated polypeptide of 250 kDa; MGC176453;
Gene ID : 57697
mRNA Refseq : NM_020937
Protein Refseq : NP_065988
MIM : 609644
UniProt ID : Q8IYD8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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